Mast cell activation in sterile bladder and prostate inflammation.

  title={Mast cell activation in sterile bladder and prostate inflammation.},
  author={Theoharis C Theoharides and Nikolaos Flaris and Claire T. Cronin and Angelo A. Ucci and E M Meares},
  journal={International archives of allergy and applied immunology},
  volume={92 3},
Sterile inflammation of the bladder has often been associated with interstitial cystitis (IC), a urologic condition of unknown etiology, predominantly affecting young and middle-aged females, for which no effective therapy is known. Recent reports have indicated that IC is associated with an increased number of bladder mast cells. Here we report the case of a middle-aged man with chronic sterile hematuria, dysuria and lower abdominal pain associated with a high number of bladder and prostate… CONTINUE READING