Massive parallel MHC genotyping: titanium that shines.

@article{Wegner2009MassivePM,
  title={Massive parallel MHC genotyping: titanium that shines.},
  author={K Mathias Wegner},
  journal={Molecular ecology},
  year={2009},
  volume={18 9},
  pages={1818-20}
}
The power of population genetic analyses is often limited by sample size resulting from constraints in financial resources and time to genotype large numbers of individuals. This particularly applies to nonmodel species where detailed genomic knowledge is lacking. Next-generation sequencing technology using primers 'tagged' with an individual barcode of a few nucleotides offers the opportunity to genotype hundreds of individuals at several loci in parallel (Binladen et al. 2007; Meyer et al… CONTINUE READING