Massive loss of sulfur in HIV infection.

  title={Massive loss of sulfur in HIV infection.},
  author={Raoul Breitkreutz and Stefanie Holm and Nicole Pittack and Matthias Beichert and Alexander Babylon and Juni Yodoi and Wulf Dr{\"o}ge},
  journal={AIDS research and human retroviruses},
  volume={16 3},
Skeletal muscle tissue from SIV-infected macaques was previously found to contain abnormally high sulfate and low glutathione levels indicative of an excessive cysteine catabolism. We now confirm the peripheral tissue as a site of massive cysteine catabolism in HIV infection and have determined the urinary loss of sulfur per time unit. The comparison of the sulfate concentrations of the arterial and venous blood from the lower extremities of 16 symptomatic HIV+ patients and 18 HIV- control… CONTINUE READING