Massive expansion and functional divergence of innate immune genes in a protostome

@inproceedings{Zhang2015MassiveEA,
  title={Massive expansion and functional divergence of innate immune genes in a protostome},
  author={Linlin Zhang and Li Li and Ximing Guo and Gary W. Litman and Larry J Dishaw and Guofan Zhang},
  booktitle={Scientific reports},
  year={2015}
}
The molecules that mediate innate immunity are encoded by relatively few genes and exhibit broad specificity. Detailed annotation of the Pacific oyster (Crassostrea gigas) genome, a protostome invertebrate, reveals large-scale duplication and divergence of multigene families encoding molecules that effect innate immunity. Transcriptome analyses indicate dynamic and orchestrated specific expression of numerous innate immune genes in response to experimental challenge with pathogens, including… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 13 times over the past 90 days. VIEW TWEETS
40 Citations
63 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 40 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 63 references

Toll-like receptors and MyD88 adaptors in Mytilus: Complete cds and gene expression levels

  • M Toubiana
  • Developmental & Comparative Immunology
  • 2013

Similar Papers

Loading similar papers…