Massive and disproportionate elevation of blood urea nitrogen in acute azotemia

@article{Feinfeld2004MassiveAD,
  title={Massive and disproportionate elevation of blood urea nitrogen in acute azotemia},
  author={Donald A. Feinfeld and Hiba Bargouthi and Q Niaz and Christos P. Carvounis},
  journal={International Urology and Nephrology},
  year={2004},
  volume={34},
  pages={143-145}
}
In renal failure, blood urea nitrogen and serumcreatinine usually rise in tandem; the normalBUN : Cr ratio is 10–15 : 1. Disproportionate risesin BUN : Cr (> 20 : 1) often imply pre-renalazotemia but may be caused by increased proteincatabolism or an excessive protein load. Inthis study we looked at intensive care patientswho acutely developed markedly increased BUN(≥ 100 mg/dL) with only modestelevation of Cr (≤ 5 mg/dL) forpossible causes of the disproportionateazotemia. There were 19 such… 

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A case of extreme azotaemia

A patient with remarkable biochemical derangement is presented, especially high BUN, which has not previously been seen in the department, nor described in the literature.

The fallacy of the BUN:creatinine ratio in critically ill patients.

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  • 2012
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Usefulness of BUN/Albumin Ratio in Prediction of 28-day Mortality in Patients with Acute Cholangitis

The ratio of BUN to albumin on ED admission is a promising prognostic marker of 28-day mortality in patients with acute cholangitis.

Acute Kidney Injury Masked by Malnutrition: A Case Report and the Problem of Protein.

It is concluded that the available evidence suggests that significant restrictions in protein intake are not necessary for those critically ill patients with AKI, and further research is needed to systematically determine the optimal dose of protein for critically ill adults withAKI.

NT-ProBNP and cardiac troponin I in virulent canine babesiosis.

Influence of sub-chronic oral exposure to high monosodium glutamate on some serum markers of the renal functions in male Wistar rats

Exposure to MSG significantly altered the renal functions in rats by way of compromised urea and creatinine metabolism, and the nutritional and health implications of the results may be significant in animals and therefore warrant further and better controlled investigation in humans.

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