Massive acetylcysteine overdose associated with cerebral edema and seizures.

CONTEXT Acetylcysteine is a safe and effective treatment for the prevention of hepatic injury due to acetaminophen poisoning. While dosing errors are common, in most cases, overdoses produce minimal clinical effects. CASE REPORT We describe a patient who received 150 g of IV acetylcysteine over 32 h when the clinician ordered the infusion doses be… (More)