Massive Ibuprofen Ingestion with Survival

@article{Seifert2000MassiveII,
  title={Massive Ibuprofen Ingestion with Survival},
  author={S. Seifert and A. Bronstein and T. Mcguire},
  journal={Journal of Toxicology: Clinical Toxicology},
  year={2000},
  volume={38},
  pages={55 - 57}
}
  • S. Seifert, A. Bronstein, T. Mcguire
  • Published 2000
  • Medicine
  • Journal of Toxicology: Clinical Toxicology
  • Objective: To report a massive, 100 g ibuprofen ingestion in an adolescent, with survival. Case Report: The patient developed coma, metabolic acidosis, and mild thrombocytopenia, but improved rapidly with supportive care. Renal function remained normal and no gastrointestinal bleeding occurred. Conclusions: Massive ingestion of ibuprofen may result in a variable picture with some elements of significant toxicity, but supportive care usually results in survival without sequelae. 
    27 Citations
    Serious toxicity in a young child due to ibuprofen.
    • 27
    A report of two deaths from massive ibuprofen ingestion
    • 22
    • PDF
    Nonsteroidal Anti-Inflammatory Drug Toxicity in Children: A Clinical Review
    • 6
    Nonsteroidal Anti-Inflammatory Drug Toxicity in Children: A Clinical Review
    • E. Chung
    • Medicine
    • Pediatric emergency care
    • 2016
    • 1
    An overview of clinical pharmacology of Ibuprofen.
    • 160
    • PDF
    Ibuprofen-induced hypersensitivity syndrome.
    • R. Nanau, M. Neuman
    • Medicine
    • Translational research : the journal of laboratory and clinical medicine
    • 2010
    • 29
    Over-the-counter Analgesics: A Toxicologic Perspective
    • A. Jones
    • Medicine
    • American journal of therapeutics
    • 2002
    • 44
    Repurposing of Aspirin and Ibuprofen as Candidate Anti-Cryptococcus Drugs
    • 26
    • PDF

    References

    SHOWING 1-10 OF 12 REFERENCES
    Acute oliguric renal failure due to ibuprofen overdose.
    • 8
    Acute Poisoning with Ibuprofen
    • 35
    Acute intoxication due to ibuprofen overdose.
    • 50
    Ibuprofen overdose in adults.
    • 22
    Metabolic acidosis after acute ibuprofen overdosage.
    • 36
    Ibuprofen overdose: 126 cases.
    • 46
    • Highly Influential
    • PDF
    Tissue distribution of ibuprofen in a fatal overdose.
    • 30
    The Relationship between Plasma Ibuprofen Concentrations and Toxicity in Acute Ibuprofen Overdose
    • 19
    Ibuprofen overdose
    • 23