Massign: an assignment strategy for maximizing information from the mass spectra of heterogeneous protein assemblies.

@article{Morgner2012MassignAA,
  title={Massign: an assignment strategy for maximizing information from the mass spectra of heterogeneous protein assemblies.},
  author={Nina Morgner and Carol V Robinson},
  journal={Analytical chemistry},
  year={2012},
  volume={84 6},
  pages={2939-48}
}
Electrospray ionization mass spectrometry (ESI-MS) has evolved into a powerful adjunct for structural biology, helping to unravel the quaternary structure of protein complexes. Increasing interest has led to the study of ever larger multicomponent systems. Investigating these large complexes with ESI has meant that progressively more complicated mass spectra have been recorded. Correct assignment of these spectra is essential to maximize the information content available. Here we present a new… CONTINUE READING

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