Mass uptake study of the diffusion of water and SBF into poly(2-hydroxyethyl methacrylate-co-tetrahydrofurfuryl methacrylate) containing aspirin or vitamin B12

@article{Chowdhury2005MassUS,
  title={Mass uptake study of the diffusion of water and SBF into poly(2-hydroxyethyl methacrylate-co-tetrahydrofurfuryl methacrylate) containing aspirin or vitamin B12},
  author={Mohammad A. Chowdhury and D. J. Hill and A. Whittaker},
  journal={Journal of Biomaterials Science, Polymer Edition},
  year={2005},
  volume={16},
  pages={1047 - 1061}
}
The ingress of water and Kokubo simulated body fluid (SBF) into poly(2-hydroxyethyl methacrylate) (PHEMA), and its co-polymers with tetrahydrofurduryl methacrylate (THFMA), loaded with either one of two model drugs, vitamin B12 or aspirin, was studied by mass uptake over the temperature range 298–318 K. The polymers were studied as cylinders and were loaded with either 5 wt% or 10 wt% of the drugs. From DSC studies it was observed that vitamin B12 behaved as a physical cross-linker restricting… Expand
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