Mass spectrometry to complement standardization of house dust mite and other complex allergenic extracts.

@article{Spiric2017MassST,
  title={Mass spectrometry to complement standardization of house dust mite and other complex allergenic extracts.},
  author={Jelena Spiric and Andreas Reuter and Ronald L Rabin},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={2017},
  volume={47 5},
  pages={604-617}
}
In the United States, the Center for Biologics Evaluation and Research of the US Food and Drug Administration regulates biologics used for diagnosis and treatment of allergic diseases. The Code of Federal Regulations 21CFR680.3(e) states that when measured, the potency of an allergenic extract is assessed according to its allergenic activity. As of 2016, 19 allergenic extracts are standardized for potency in the United States. While these standardized extracts constitute a minority of those… CONTINUE READING