Mass spectrometry for the evaluation of cardiovascular diseases based on proteomics and lipidomics.

  title={Mass spectrometry for the evaluation of cardiovascular diseases based on proteomics and lipidomics.},
  author={A. Thomas and S. Lenglet and P. Chaurand and J. D{\'e}glon and P. Mangin and F. Mach and S. Steffens and J. Wolfender and C. Staub},
  journal={Thrombosis and haemostasis},
  volume={106 1},
  • A. Thomas, S. Lenglet, +6 authors C. Staub
  • Published 2011
  • Medicine
  • Thrombosis and haemostasis
  • The identification and quantification of proteins and lipids is of major importance for the diagnosis, prognosis and understanding of the molecular mechanisms involved in disease development. Owing to its selectivity and sensitivity, mass spectrometry has become a key technique in analytical platforms for proteomic and lipidomic investigations. Using this technique, many strategies have been developed based on unbiased or targeted approaches to highlight or monitor molecules of interest from… CONTINUE READING
    40 Citations
    The emerging role of plasma lipidomics in cardiovascular drug discovery
    • 20
    A vision for better health: mass spectrometry imaging for clinical diagnostics.
    • 22
    Trends in mass spectrometry imaging for cardiovascular diseases
    • 8
    • PDF
    Metabolomics and ischaemic heart disease.
    • 35
    • PDF
    MALDI TOF imaging mass spectrometry in clinical pathology: a valuable tool for cancer diagnostics (review).
    • 90
    • PDF
    Phospholipids as cancer biomarkers: Mass spectrometry-based analysis.
    • 58


    Mass spectrometry: from proteomics to metabolomics and lipidomics.
    • W. Griffiths, Yuqin Wang
    • Chemistry, Medicine
    • Chemical Society reviews
    • 2009
    • 217
    • Highly Influential
    • PDF
    Candidate‐based proteomics in the search for biomarkers of cardiovascular disease
    • L. Anderson
    • Medicine, Biology
    • The Journal of physiology
    • 2005
    • 368
    • PDF
    Proteomic strategies in the search of new biomarkers in atherothrombosis.
    • 37
    • PDF
    New developments in profiling and imaging of proteins from tissue sections by MALDI mass spectrometry.
    • 252
    Chemometrics in metabolomics--a review in human disease diagnosis.
    • 447
    Proteomics-based Development of Biomarkers in Cardiovascular Disease
    • 87
    • PDF
    Mass spectrometry-based metabolomics.
    • 1,521
    • Highly Influential
    • PDF
    MALDI Imaging Mass Spectrometry
    • 139
    • PDF
    Lipidomics: A Tool for Studies of Atherosclerosis
    • 79
    • PDF
    Perspectives of targeted mass spectrometry for protein biomarker verification.
    • 157