Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors.

@article{Denkert2006MassSM,
  title={Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors.},
  author={C. Denkert and J. Budczies and T. Kind and W. Weichert and P. Tablack and J. Sehouli and S. Niesporek and D. Könsgen and M. Dietel and O. Fiehn},
  journal={Cancer research},
  year={2006},
  volume={66 22},
  pages={
          10795-804
        }
}
Metabolites are the end products of cellular regulatory processes, and their levels can be regarded as the ultimate response of biological systems to genetic or environmental changes. We have used a metabolite profiling approach to test the hypothesis that quantitative signatures of primary metabolites can be used to characterize molecular changes in ovarian tumor tissues. Sixty-six invasive ovarian carcinomas and nine borderline tumors of the ovary were analyzed by gas chromatography/time-of… Expand
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