Mass spectrometry analysis of transthyretin (TTR) post-translational modifications (PTMs) in hereditary ATTR: a case-control Spanish experience

Abstract

Background Transthyretin (TTR) is an amyloidogenic tetrameric protein, present in human plasma, associated with several familial amyloidoses. Variability of TTR is not only due to point mutations in the encoding gene but also to post-translational modifications (PTMs) at Cys10, being the most common PTMs the S-sulfonation, S-glycinylcysteinylation, S… (More)

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Cite this paper

@inproceedings{VilRico2015MassSA, title={Mass spectrometry analysis of transthyretin (TTR) post-translational modifications (PTMs) in hereditary ATTR: a case-control Spanish experience}, author={Marta Vil{\`a}-Rico and Sebasti{\'a}n E Azor{\'i}n Contesse and Jos{\'e} E Barcena Llona and Ricard Rojas-Garcia and Fernando Mart{\'i}nez Valle and Antoni Planas and Francesc V Canals and Josep Mar{\'i}a Campistol}, year={2015} }