Mass spectrometry: from proteomics to metabolomics and lipidomics.

  title={Mass spectrometry: from proteomics to metabolomics and lipidomics.},
  author={W. Griffiths and Yuqin Wang},
  journal={Chemical Society reviews},
  volume={38 7},
  • W. Griffiths, Yuqin Wang
  • Published 2009
  • Chemistry, Medicine
  • Chemical Society reviews
  • Mass spectrometry (MS) in combination with liquid chromatography (LC), i.e. LC-MS, is the key analytical technique on which the emerging "omics" technologies of proteomics, metabolomics and lipidomics are based. It provides both structural and quantitative data and can be used in a "global" or "targeted" manner allowing on the one hand the identification of thousands of proteins from a tissue, or on the other the detection of biologically active metabolites at levels of a few parts-per-billion… CONTINUE READING
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