Mass spectrometric identification of 2-hydroxydodecanedioic acid and its homologues in urine from patients with hopantenate therapy during clinical episode.

@article{Matsumoto1990MassSI,
  title={Mass spectrometric identification of 2-hydroxydodecanedioic acid and its homologues in urine from patients with hopantenate therapy during clinical episode.},
  author={M. Matsumoto and T. Kuhara and Y. Inoue and T. Shinka and I. Matsumoto and M. Kajita},
  journal={Biomedical & environmental mass spectrometry},
  year={1990},
  volume={19 3},
  pages={
          171-5
        }
}
  • M. Matsumoto, T. Kuhara, +3 authors M. Kajita
  • Published 1990
  • Chemistry, Medicine
  • Biomedical & environmental mass spectrometry
  • Urine from patients with calcium-4-(2,4-dihydroxy-3,3-dimethylbutyramido) butyrate hemihydrate (hopantenate) therapy during episodes of Reye's-like syndrome was found to contain a number of unusual dicarboxylic acids in high concentrations; odd- and even-numbered medium-chain dicarboxylic acids, alpha-hydroxydicarboxylic acids and beta-hydroxydicarboxylic acids. The abnormal excretion of dicarboxylic acids, alpha- and beta-hydroxydicarboxylic acids disappeared after discontinuance of… CONTINUE READING
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