Mass spectrometric fragmentation analysis of oligosialic and polysialic acids.

@article{Galuska2010MassSF,
  title={Mass spectrometric fragmentation analysis of oligosialic and polysialic acids.},
  author={Sebastian P Galuska and Hildegard Geyer and Christina Bleckmann and Ren{\'e} C R{\"o}hrich and K. A. Maass and Anne K. Bergfeld and Martina M{\"u}hlenhoff and Rudolf Geyer},
  journal={Analytical chemistry},
  year={2010},
  volume={82 5},
  pages={2059-66}
}
Oligosialic and polysialic acids (oligo/polySia) are characterized by high structural diversity, because of different types of sialic acids and glycosidic linkages. Although several methods have been described for the analysis of oligo/polySia, only high-performance liquid chromatography (HPLC) analysis in conjunction with 1,2-diamino-4,5-methylenedioxybenzene labeling, fluorometric C7/C9 detection, Western blotting, and matrix-assisted laser desorption/ionization time-of-flight mass… CONTINUE READING