Mass spectrometric based approaches in urine metabolomics and biomarker discovery.

  title={Mass spectrometric based approaches in urine metabolomics and biomarker discovery.},
  author={Mona M. Khamis and Darryl Adamko and Anas El-Aneed},
  journal={Mass spectrometry reviews},
  volume={36 2},
Urine metabolomics has recently emerged as a prominent field for the discovery of non-invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific disease or therapeutic intervention. Urine, compared to other biofluids, is characterized by its ease of collection, richness in metabolites and its ability to reflect imbalances of all biochemical pathways within the body. Following urine collection for metabolomic analysis, samples must be immediately frozen to… CONTINUE READING
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