Mass spectral fragmentation pathways of propranolol related beta-fluorinated amines studied by electrospray and electron impact ionization.

@article{Upthagrove1999MassSF,
  title={Mass spectral fragmentation pathways of propranolol related beta-fluorinated amines studied by electrospray and electron impact ionization.},
  author={A L Upthagrove and Murray Hackett and W. L. Nelson},
  journal={Rapid communications in mass spectrometry : RCM},
  year={1999},
  volume={13 16},
  pages={1671-9}
}
Propranolol, its 1"-mono-, di-, and trifluorinated analogs, and other related compounds were analyzed under electrospray ionization ion trap collision-induced dissociation (ESI-CID) and electron impact (EI) conditions. Interesting trends were observed in the fragment ions formed in both cases. Under ESI conditions, the abundances of product ions easily explained by protonation on the amine nitrogen decreased relative to the abundances of those formed from the ether-protonated species as the… CONTINUE READING