Mass Spectrometry-Based Proteomic Analyses in Contact Lens-Related Dry Eye

  title={Mass Spectrometry-Based Proteomic Analyses in Contact Lens-Related Dry Eye},
  author={J. Nichols and K. Green-Church},
  • J. Nichols, K. Green-Church
  • Published 2009
  • Chemistry, Medicine
  • Cornea
  • Purpose: To identify potential protein biomarkers associated with dry eye in contact lens wearers. Methods: Upon enrollment, current galyfilcon A contact lens wearers completed a previously described questionnaire used to classify dry eye status. Approximately 5 μL of aqueous tears were carefully sampled from the inferior-lateral tear prism of each eye using glass microcapillaries. A variety of proteomic approaches were used to compare samples including quantification by Bradford analyses… CONTINUE READING
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