Mass Spectrometry-Based Metabolomics Reveals Occupational Exposure to Per- and Polyfluoroalkyl Substances Relates to Oxidative Stress, Fatty Acid β-Oxidation Disorder, and Kidney Injury in a Manufactory in China.

  title={Mass Spectrometry-Based Metabolomics Reveals Occupational Exposure to Per- and Polyfluoroalkyl Substances Relates to Oxidative Stress, Fatty Acid $\beta$-Oxidation Disorder, and Kidney Injury in a Manufactory in China.},
  author={Yao Lu and Ke Gao and Xiaona Li and Zhi Tang and Li Xiang and Hongzhi Zhao and Jianjie Fu and Ling Wang and Nali Zhu and Zongwei Cai and Yong Liang and Yawei Wang and Guibin Jiang},
  journal={Environmental science \& technology},
  • Yao LuKe Gao G. Jiang
  • Published 17 June 2019
  • Medicine
  • Environmental science & technology
Occupational workers are usually exposed to high levels of per- and polyfluoroalkyl substances (PFASs), placing them under greater health risks compared to the general population. Herein, 40 occupational workers from a factory in China and 52 control subjects from the general population were involved in an investigation on the potential health concerns of occupational exposure to PFASs by mass spectrometry-based metabolomics analysis. The PFAS levels in plasma from both groups were analyzed… 

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