Mask-based approach to phasing of single-particle diffraction data.

  title={Mask-based approach to phasing of single-particle diffraction data.},
  author={V. Lunin and N. Lunina and T. Petrova and M. Baumstark and A. Urzhumtsev},
  journal={Acta crystallographica. Section D, Structural biology},
  volume={72 Pt 1},
A Monte Carlo-type approach for low- and medium-resolution phasing of single-particle diffraction data is suggested. Firstly, the single-particle phase problem is substituted with the phase problem for an imaginary crystal. A unit cell of this crystal contains a single isolated particle surrounded by a large volume of bulk solvent. The developed phasing procedure then generates a large number of connected and finite molecular masks, calculates their Fourier coefficients, selects the sets with… Expand

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