Masitinib for the treatment of canine atopic dermatitis: a pilot study

  title={Masitinib for the treatment of canine atopic dermatitis: a pilot study},
  author={Jenise C Daigle and Alain Moussy and Colin D. Mansfield and Olivier Hermine},
  journal={Veterinary Research Communications},
There is an on-going need to identify medications suitable for the long-term treatment of canine atopic dermatitis (CAD). Masitinib mesilate is a potent and selective tyrosine kinase inhibitor of the c-KIT receptor. A strong relationship exists between the SCF/c-KIT pathway and pathogenesis of CAD, suggesting that masitinib may potentially fulfil the above role. This study reports on an uncontrolled pilot study of masitinib in CAD. Masitinib was administered orally to 11 dogs at a mean dose of… CONTINUE READING
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