Marrow-inspired matrix cues rapidly affect early fate decisions of hematopoietic stem and progenitor cells

Abstract

Hematopoiesis is the physiological process where hematopoietic stem cells (HSCs) continuously generate the body's complement of blood and immune cells within unique regions of the bone marrow termed niches. Although previous investigations have revealed gradients in cellular and extracellular matrix (ECM) content across the marrow, and matrix elasticity and… (More)
DOI: 10.1126/sciadv.1600455

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Cite this paper

@inproceedings{Choi2017MarrowinspiredMC, title={Marrow-inspired matrix cues rapidly affect early fate decisions of hematopoietic stem and progenitor cells}, author={Ji Sun Choi and Brendan A C Harley}, booktitle={Science advances}, year={2017} }