Marrow fibrosis predicts early fatal marrow failure in patients with myelodysplastic syndromes

@article{Bsche2008MarrowFP,
  title={Marrow fibrosis predicts early fatal marrow failure in patients with myelodysplastic syndromes},
  author={Guntram B{\"u}sche and Huesniye Teoman and Waldemar Wilczak and Arnold Ganser and Hartmut Hecker and L. Wilkens and Gudrun G{\"o}hring and Brigitte Schlegelberger and Oliver Bock and Axel Georgii and H Kreipe},
  journal={Leukemia},
  year={2008},
  volume={22},
  pages={313-322}
}
Marrow fibrosis (MF) has rarely been studied in myelodysplastic syndromes (MDS). There are no data on occurrence and significance of MF in the context of the World Health Organization (WHO) classification of disease. In total, 349 bone marrow biopsies from 200 patients with primary MDS were examined for MF and its prognostic relevance. MF correlated with multilineage dysplasia, more severe thrombopenia, higher probability of a clonal karyotype abnormality, and higher percentages of blasts in… CONTINUE READING
23 Citations
41 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Similar Papers

Loading similar papers…