Marrow changes in paraplegic patients

@article{Minaire1984MarrowCI,
  title={Marrow changes in paraplegic patients},
  author={P M Minaire and Claude M. Edouard and Monique Arlot and Pierre Jean Meunier},
  journal={Calcified Tissue International},
  year={1984},
  volume={36},
  pages={338-340}
}
Immobilization leads to a rapid bone loss resulting from both an increased bone resorption, and a decreased bone formation (I). In complete paralysis following spinal cord injury, 33 % of the iliac trabeeular bone is lost over 6 months, before a new steady state without further loss is reached (I). The excretion of calcium and hydroxyproline declines over this same period from initial high values to reach stable, but elevated levels. In both humans and laboratory animals these changes are very… CONTINUE READING
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