Markov modeling analysis of health and economic outcomes of therapy with valsartan versus amlodipine in patients with type 2 diabetes and microalbuminuria.

@article{Smith2004MarkovMA,
  title={Markov modeling analysis of health and economic outcomes of therapy with valsartan versus amlodipine in patients with type 2 diabetes and microalbuminuria.},
  author={Dean G. Smith and Anh Bao Nguyen and Corey N Peak and Feride H Frech},
  journal={Journal of managed care pharmacy : JMCP},
  year={2004},
  volume={10 1},
  pages={26-32}
}
OBJECTIVE To estimate 8-year health and economic outcomes of the angiotensin II receptor blocker valsartan versus the calcium channel blocker amlodipine in therapy of patients with type 2 diabetes and microalbuminuria based on clinical endpoints from a 6-month randomized controlled clinical trial, the MicroAlbuminuria Reduction With VALsartan (MARVAL) study. METHODS We developed a Markov model that utilized urinary albumin excretion rate data to project patient distributions to 7 possible… CONTINUE READING
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