Markov Chain Monte Carlo Methods for Radiation Hybrid Mapping

@article{Heath1997MarkovCM,
  title={Markov Chain Monte Carlo Methods for Radiation Hybrid Mapping},
  author={S. C. Heath},
  journal={Journal of computational biology : a journal of computational molecular cell biology},
  year={1997},
  volume={4 4},
  pages={505-15}
}
The ordering of genetic loci is central to genetic mapping at all levels. Markov chain Monte Carlo (MCMC) techniques can provide estimates of the posterior density of orders while accounting naturally for missing data, data errors, and unknown parameters. MCMC sampling schemes have been proposed for mapping problems such as linkage mapping and radiation… CONTINUE READING