Markers of proliferation in normal and leukoplakic oral epithelia.

  title={Markers of proliferation in normal and leukoplakic oral epithelia.},
  author={S C Liu and Andres J. P. Klein-Szanto},
  journal={Oral oncology},
  volume={36 2},
We have reviewed the recent literature on immunohistochemical markers of cell proliferation in normal oral epithelia and leukoplakias. Most findings, including our own, point to an increased proliferation in oral leukoplakias that correlates with the degree of dysplasia. Although the basal layer of normal oral epithelia showed a very low proliferative activity, oral leukoplakias, even those containing low-grade dysplasia, exhibited a very significant increase in proliferation. High-grade… CONTINUE READING

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