Markers of epithelial-mesenchymal transition in renal cell carcinoma.

  title={Markers of epithelial-mesenchymal transition in renal cell carcinoma.},
  author={Yuriy V Dumanskiy and A G Kudriashov and Inna V. Vasilenko and R B Kondratyuk and Y K Gulkov and R S Cyrillichystiakov},
  journal={Experimental oncology},
  volume={35 4},
AIM To study the influence of markers of epithelial-mesenchymal transition (EMT) on a renal cell carcinoma (RCC) prognosis. METHODS The surgical material of 47 RCC patients who underwent nephrectomy was studied. RCC patients were distributed in two groups: a short-term survival group (3-6 months) and a long-term survival group (17-24 months). EMT markers expression was assessed by immunohistochemical methods. RESULTS It was determined that the rate of spindle-cell EMT was 96.4% in a short… CONTINUE READING

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