Marker chromosomes in a series of 10,000 prenatal diagnoses. Cytogenetic and follow-up studies.

@article{Sachs1987MarkerCI,
  title={Marker chromosomes in a series of 10,000 prenatal diagnoses. Cytogenetic and follow-up studies.},
  author={Eva S. Sachs and Johan Van hemel and Jan Christiaan den Hollander and Maddalena Jahoda},
  journal={Prenatal diagnosis},
  year={1987},
  volume={7 2},
  pages={81-9}
}
In a series of 10,000 prenatal diagnoses 15 marker chromosomes were detected in our centre. Six of these were familial whilst nine had originated de novo. They were analysed with various staining methods. DA-DAPI staining was positive in nine out of 12 pregnancies. Six pregnancies were continued. Five normal children were born, one ended in intrauterine fetal death of a normal fetus at 37 weeks. Nine pregnancies were terminated, showing six normal fetuses, one familial cat-eye syndrome, one… CONTINUE READING

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