Marked variation in antiphospholipid antibodies during pregnancy: relationships to pregnancy outcome.

@article{Topping1999MarkedVI,
  title={Marked variation in antiphospholipid antibodies during pregnancy: relationships to pregnancy outcome.},
  author={Joanne Topping and Siobhan Quenby and Roy G. Farquharson and Ram{\'o}n Mali{\'a} and Michael Greaves},
  journal={Human reproduction},
  year={1999},
  volume={14 1},
  pages={224-8}
}
Variations in blood concentrations of antiphospholipid antibodies (APA) were investigated through the course of pregnancy in women who had a history of recurrent pregnancy loss, and were related to changes in pregnancy outcome. Serial measurements of APA were made in 16 women with antiphospholipid syndrome (APS) and 16 with negative APA tests pre-pregnancy. There was considerable intraindividual variation in test results through pregnancy. There was a significantly higher ratio of dilute… CONTINUE READING

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