Marked up-regulation of T lymphocytes and expression of interleukin-9 in bronchial biopsies from patients With chronic bronchitis with obstruction.

@article{Panzner2003MarkedUO,
  title={Marked up-regulation of T lymphocytes and expression of interleukin-9 in bronchial biopsies from patients With chronic bronchitis with obstruction.},
  author={Petr Panzner and J Y Lafitte and Anne Tsicopoulos and Qutayba A. Hamid and Meri Katarina Tulic},
  journal={Chest},
  year={2003},
  volume={124 5},
  pages={1909-15}
}
STUDY OBJECTIVE To examine the differences in the inflammatory cell and cytokine profile between patients with chronic bronchitis (CB) with and without airway obstruction compared to control subjects. DESIGN We used bronchial biopsy samples from the patients and control subjects and analyzed them for the presence of CD3 T cells, CD68, major basic protein (MBP), elastase, and tryptase, as well as expression of messenger RNA (mRNA) coding for interleukin (IL)-4, IL-5, interferon (IFN)-gamma, IL… CONTINUE READING