Marked loss of myelinated nerve fibers in the human brain with age

  title={Marked loss of myelinated nerve fibers in the human brain with age},
  author={L. Marner and J. Nyengaard and Yong Tang and B. Pakkenberg},
  journal={Journal of Comparative Neurology},
  • L. Marner, J. Nyengaard, +1 author B. Pakkenberg
  • Published 2003
  • Biology, Medicine
  • Journal of Comparative Neurology
  • The white matter is the structure of the brain that declines most with age—almost 30%, but little is known about the age‐effect on the fibers that constitute the white matter. In the present study, the total length of myelinated fibers was measured with a newly developed stereologic method. Specimens came from 36 normal Danes (18 males and 18 females) with an age ranging between 18 and 93 years. Samples were taken systematically and randomly from the white matter, and the biopsy specimens were… CONTINUE READING
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