Marked induction of hepatocyte growth factor mRNA in intact kidney and spleen in response to injury of distant organs.

@article{Kono1992MarkedIO,
  title={Marked induction of hepatocyte growth factor mRNA in intact kidney and spleen in response to injury of distant organs.},
  author={Suminori Kono and M Nagaike and Kazuya Matsumoto and Toshikazu Nakamura},
  journal={Biochemical and biophysical research communications},
  year={1992},
  volume={186 2},
  pages={991-8}
}
Hepatocyte growth factor (HGF) is a potent mitogen for various epithelial cells, including mature hepatocytes and renal tubular cells. Here, HGF mRNA was found to be markedly increased in non-injured kidney and spleen, when the liver or kidney in rats was injured by 70% partial hepatectomy or unilateral nephrectomy. HGF mRNA increased to 3-4 fold higher level than the normal in the kidney and spleen as well as in the remnant liver after partial hepatectomy. Similarly, HGF mRNA markedly… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

Similar Papers

Loading similar papers…