Marked increase of CD8+S6F1+ and CD8+CD57+ cells in patients with graft-versus-host disease after allogeneic bone marrow transplantation.

@article{Fukuda1994MarkedIO,
  title={Marked increase of CD8+S6F1+ and CD8+CD57+ cells in patients with graft-versus-host disease after allogeneic bone marrow transplantation.},
  author={Haruhiko Fukuda and Hironobu Nakamura and Nobuhiko Tominaga and Hirofumi Teshima and Akira Hiraoka and Hironobu Shibata and Tohru Masaoka},
  journal={Bone marrow transplantation},
  year={1994},
  volume={13 2},
  pages={
          181-5
        }
}
Peripheral blood lymphocytes (PBL) from 24 allogeneic bone marrow transplant (BMT) recipients were studied serially using flow cytometry and two-color analysis. Dual labelling with two monoclonal antibodies (moAbs), CD8/S6F1 (CD11a) and CD8/CD57 was used to analyze the surface phenotypes of PBL after allogeneic BMT. In patients with acute and chronic GVHD, CD8+S6F1+ cells were markedly increased from the onset of GVHD and recovered to normal range 6 years after transplantation. By contrast, CD8… CONTINUE READING