Marked elevation of serum interleukin-6 in patients with cholangiocarcinoma: validation of utility as a clinical marker.


OBJECTIVE To determine if the serum level of interleukin-6 (IL-6) was elevated in patients with hepatic malignancies or correlated with radiologic tumor burden. SUMMARY BACKGROUND DATA High serum levels of IL-6 signify an adverse prognosis in many patients with cancer. IL-6 is a growth factor for bile duct epithelium. METHODS Using bioactive and enzyme… (More)