Marinisporolides, polyene-polyol macrolides from a marine actinomycete of the new genus Marinispora.

@article{Kwon2009MarinisporolidesPM,
  title={Marinisporolides, polyene-polyol macrolides from a marine actinomycete of the new genus Marinispora.},
  author={Hak Cheol Kwon and Christopher A. Kauffman and Paul Robert Jensen and William Fenical},
  journal={The Journal of organic chemistry},
  year={2009},
  volume={74 2},
  pages={675-84}
}
Two new polyene macrolides, marinisporolides A and B (1, 2), were isolated from the saline culture of the marine actinomycete, strain CNQ-140, identified as a member of the new marine genus Marinispora. The marinisporolides are 34-membered macrolides composed of a conjugated pentaene and several pairs of 1,3-dihydroxyl functionalities. Marinisporolide A (1) contains a bicyclic spiro-bis-tetrahydropyran ketal functionality, while marinisporolide B (2) is the corresponding hemiketal. The… CONTINUE READING

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