Marine polyprenylated hydroquinones, quinones, and chromenols with inhibitory effects on leukotriene formation.

@article{Tziveleka2005MarinePH,
  title={Marine polyprenylated hydroquinones, quinones, and chromenols with inhibitory effects on leukotriene formation.},
  author={Leto-A Tziveleka and Dennis Abatis and Kerstin Paulus and Rudolf Bauer and Constantinos Vagias and Vassilios Roussis},
  journal={Chemistry & biodiversity},
  year={2005},
  volume={2 7},
  pages={901-9}
}
A series of polyprenylated hydroquinones, quinones, and chromenols were isolated from the extracts of the marine sponge Ircinia spinosula and the brown alga Taonia atomaria, which gave rise to the constituents 1-4 and 5-8, respectively. Compounds 1, 2, 6, and 7 are new natural products, which were fully characterized. Their anti-inflammatory activities in terms of leukotriene formation were evaluated in an in vitro assay with pork leukocytes. The new hydroxylated compound, 2'-[28-hydroxy… CONTINUE READING

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Biological importance of marine algae.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society • 2010

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