Marijuana Use and the Development of Status Asthmaticus: A Case Report

@article{Alexis2012MarijuanaUA,
  title={Marijuana Use and the Development of Status Asthmaticus: A Case Report},
  author={Lanteri Alexis and Samir D. Bhangle and Kristin G. Fless},
  journal={Open Journal of Anesthesiology},
  year={2012},
  volume={2012},
  pages={62-64}
}
Introduction: Status asthmaticus is an acute exacerbation of asthma caused by increased airflow resistance and mucus plugging. Symptoms of dyspnea may lead to respiratory failure and cardiac arrest. There is limited knowledge about the effects of marijuana on pulmonary function. We report a unique case of status asthmaticus related to frequent marijuana use. Case Presentation: A 38-year-old African American male with a past medical history of asthma and two prior episodes of status asthmaticus… 
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References

SHOWING 1-10 OF 17 REFERENCES

Effects of marijuana smoking on pulmonary function and respiratory complications: a systematic review.

Physiologic data were inconclusive regarding an association between long-term marijuana smoking and airflow obstruction measures, and short-term exposure to marijuana is associated with bronchodilation.

Subacute effects of heavy marihuana smoking on pulmonary function in healthy men.

It is suggested that customary social use of marihuana may not result in detectable functional respiratory impairment in healthy young men, whereas very heavy marihana smoking for six to eight weeks causes mild but statistically significant airway obstruction.

Pulmonary effects of illicit drug use.

Effects of smoked marijuana in experimentally induced asthma.

After experimental induction of acute bronchospasm in 8 subjects with clinically stable bronchial asthma, effects of 500 mg of smoked marijuana on specific airway conductance and thoracic gas volume were compared with those of 500mg of smoked placebo marijuana, and 2.0 per cent marijuana and isoproterenol caused an immediate reversal of exercise-induced asthma and hyperinflation.

Pulmonary hazards of smoking marijuana as compared with tobacco.

It is concluded that smoking marijuana, regardless of tetrahydrocannabinol content, results in a substantially greater respiratory burden of carbon monoxide and tar than smoking a similar quantity of tobacco.

Pneumorachis and pneumomediastinum caused by repeated Müller's maneuvers: complications of marijuana smoking.

A case in which barotrauma resulted from repeated deep inspiration through a device with airflow resistance equivalent to Müller's maneuver, and combined with subcutaneous emphysema and pneumorachis occurred, without identified pneumothorax.

The epidemiology of smoking: health consequences and benefits of cessation.

Since smoking duration is the principal risk factor for smoking-related morbidity, the treatment goal should be early cessation and prevention of relapse.

The effects of smoking marihuana on physical performance.

There were significant differences between the marihuana treatment group and the other treatment groups in heart rate, systolic and diastolic blood pressure and physical work capacity.

Large lung bullae in marijuana smokers

Four men with multiple large upper zone lung bullae but otherwise relatively preserved lung parenchyma had a history of significant exposure to marijuana, suggesting a possible causal role for marijuana in the pathogenesis of this unusual pattern of bullous emphysema.

Oxidative stress produced by marijuana smoke. An adverse effect enhanced by cannabinoids.

It is concluded that MJ smoke containing Delta9-THC is a potent source of cellular oxidative stress that could contribute significantly to cell injury and dysfunction in the lungs of smokers.