Corpus ID: 4887054

Marijuana: interaction with the estrogen receptor.

@article{Sauer1983MarijuanaIW,
  title={Marijuana: interaction with the estrogen receptor.},
  author={M. Sauer and S. M. Rifka and R. Hawks and G. Cutler and D. Loriaux},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1983},
  volume={224 2},
  pages={
          404-7
        }
}
  • M. Sauer, S. M. Rifka, +2 authors D. Loriaux
  • Published 1983
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental therapeutics
  • Crude marijuana extract competed with estradiol for binding to the estrogen receptor of rat uterine cytosol. Condensed marijuana smoke also competed with estradiol for its receptor. Pure delta 9-tetrahydrocannabinol, however, did not interact with the estrogen receptor. Ten delta 9-tetrahydrocannabinol metabolites also failed to compete with estradiol for its receptor. Of several other common cannabinoids tested, only cannabidiol showed any estrogen receptor binding. This was evident only at… CONTINUE READING
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