Marijuana: Respiratory Tract Effects

@article{Owen2013MarijuanaRT,
  title={Marijuana: Respiratory Tract Effects},
  author={Kelly P. Owen and Mark E. Sutter and Timothy E. Albertson},
  journal={Clinical Reviews in Allergy \& Immunology},
  year={2013},
  volume={46},
  pages={65-81}
}
Marijuana is the most commonly used drug of abuse in the USA. It is commonly abused through inhalation and therefore has effects on the lung that are similar to tobacco smoke, including increased cough, sputum production, hyperinflation, and upper lobe emphysematous changes. However, at this time, it does not appear that marijuana smoke contributes to the development of chronic obstructive pulmonary disease. Marijuana can have multiple physiologic effects such as tachycardia, peripheral… Expand
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The medical literature so far does not support routine evaluation by pulmonary function tests or imaging studies; until more definitive data is available, it is not recommend the regular use of these tests in the evaluation of habitual marijuana smokers. Expand
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The impact of Cannabis consumption on the lungs is reviewed, taking into account that the respiratory route is the most popular route of cannabis consumption. Expand
Lung Disease Associated With Marijuana Use
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The impact of Cannabis consumption on the lungs is reviewed, taking into account that the respiratory route is the most popular route of cannabis consumption. Expand
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The current state of the science related to the adverse health effects of the recreational use of marijuana is reviewed, focusing on those areas for which the evidence is strongest. Expand
Cannabis use disorder and the lungs.
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Whereas smoking cannabis appears to increase the risk of severe bronchitis at quite low exposure, there is no convincing evidence that this leads to chronic obstructive pulmonary disease and cannabis use is associated with increased central airway resistance, lung hyperinflation, and higher vital capacity with little evidence of airflow obstruction or impairment of gas transfer. Expand
Cannabis Use and Bleomycin: An overview and case study of pulmonary toxicity
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The effects cannabis may have on the lungs, indications for cannabis use in patients with cancer, and an atypical case of progressive pulmonary toxicity in a young patient with a history of Hodgkin lymphoma and cannabis use are described. Expand
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Evidence is inconsistent regarding an association with airflow obstruction involving peripheral airways, suggesting that cannabis is unlikely to predispose to clinically significant COPD, and large-scale epidemiologic studies testing for a significant association are lacking. Expand
Marijuana: Current Concepts†
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Current research on use of Cannabis sativa and its constituents such as the cannabinoids is considered and the potential role of specific cannabinoids for medical benefit will be revealed as the twenty-first century matures. Expand
Wonder or evil?: Multifaceted health hazards and health benefits of Cannabis sativa and its phytochemicals
  • Shivika Datta, P. Ramamurthy, +12 authors Joginder Singh
  • Medicine
  • Saudi Journal of Biological Sciences
  • 2021
TLDR
This review provides insights into the various health effects of Cannabis and its specialized metabolites and indicates how wise steps can be taken to promote good use and prevent misuse of the metabolites derived from this plant. Expand
Cannabis and Lung Health: Does the Bad Outweigh the Good?
TLDR
This article will review some of the respiratory complications to cannabis use, which include lung function changes, lung destruction, increased risk of lung and head and neck cancer, and others. Expand
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References

SHOWING 1-10 OF 212 REFERENCES
Marijuana. Respiratory tract effects.
TLDR
Based on a higher frequency of case reports for upper airway cancer compared to bronchogenic carcinoma, marijuana smoking may have a more deleterious effect on the upper respiratory tract, however, this hypothesis remains speculative at best, pending confirmation by longitudinal studies. Expand
Effects of smoking cannabis on lung function
TLDR
The evidence that smoking cannabis leads to features of chronic obstructive pulmonary disease, such as airflow obstruction and emphysema is not convincing, however, there are numerous case reports of bullous emphySEma among cannabis smokers. Expand
Epidemiologic review of marijuana use and cancer risk.
TLDR
Assessment of the association of marijuana use and cancer risk in cohort studies and case-control studies concluded that sufficient studies are not available to adequately evaluate marijuana impact on cancer risk. Expand
Marijuana use and increased risk of squamous cell carcinoma of the head and neck.
  • Z. Zhang, H. Morgenstern, +5 authors S. Schantz
  • Medicine
  • Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • 1999
TLDR
The analysis indicated that marijuana use may interact with mutagen sensitivity and other risk factors to increase the risk of head and neck cancer. Expand
Respiratory effects of marijuana and tobacco use in a U.S. sample
TLDR
The impact of marijuana smoking on respiratory health has some significant similarities to that of tobacco smoking, and efforts to prevent and reduce marijuana use may have substantial public health benefits associated with decreased respiratory health problems. Expand
The association between marijuana smoking and lung cancer: a systematic review.
TLDR
Given the prevalence of marijuana smoking and studies predominantly supporting biological plausibility of an association ofarijuana smoking with lung cancer on the basis of molecular, cellular, and histopathologic findings, physicians should advise patients regarding potential adverse health outcomes until further rigorous studies are performed. Expand
A comparison of mainstream and sidestream marijuana and tobacco cigarette smoke produced under two machine smoking conditions.
TLDR
Mainstream marijuana smoke contained selected polycyclic aromatic hydrocarbons at concentrations lower than those found in mainstream tobacco smoke, while the reverse was the case for sidestream smoke, with PAHs present at higher concentrations in marijuana smoke. Expand
Effects of marijuana smoking on pulmonary function and respiratory complications: a systematic review.
TLDR
Physiologic data were inconclusive regarding an association between long-term marijuana smoking and airflow obstruction measures, and short-term exposure to marijuana is associated with bronchodilation. Expand
Pulmonary hazards of smoking marijuana as compared with tobacco.
TLDR
It is concluded that smoking marijuana, regardless of tetrahydrocannabinol content, results in a substantially greater respiratory burden of carbon monoxide and tar than smoking a similar quantity of tobacco. Expand
Marijuana exposure and pulmonary alterations in primates
TLDR
Several pathological alterations, including alveolitis, alveolar cell hyperplasia and granulomatous inflammation, were found with higher frequency in all cigarette- smoking groups, and other alterations, such as bronchiolitis, bronchiola squamous metaplasia, and interstitial fibrosis were found most frequently in the marijuana-smoking groups. Expand
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