Marihuana and the human electroencephalogram

  title={Marihuana and the human electroencephalogram},
  author={Leo E. Hollister and STEPHEN L. Sherwood and Audrey Cavasino},
  journal={Pharmacological Research Communications},

Electroencephalographic correlates of marihuana-induced euphoria.


Studies of EEG effects of Cannabis and related substances (hashish, THC) have been few, and none are definitive. In part, this is a reflection of the lack of availability of standard supplies of

Topographic Mapping of Quantitative EEG Variables in Chronic Heavy Marihuana Users: Empirical Findings with Psychiatric Patients

It is reported that chronic heavy THC users have EEGs characterized by increased absolute power of all frequencies over all cortical areas, hyperfrontality of elevated relative and absolute power and coherence values of alpha activity, and a decrease in relativePower of all non-alpha frequencies.

Acute Marihuana (THC) Exposure Produces a “Transient” Topographic Quantitative EEG Profile Identical to the “Persistent” Profile Seen in Chronic Heavy Users

All four of the topographic features of chronic THC exposure were produced as transient effects by THC but not by placebo, and this report attempts to establish the causal influence of THC in the above findings by the transient production of this exact quantitative EEG profile in subjects who did not display it at the beginning.

Electroencephalographic and evoked potential methods in human marihuana research: Historical review and future trends

The sensitivity of electroencephalographic (EEG) signals to variables affecting brain neurophysiological substrate is briefly reviewed. Because this sensitivity extends to numerous pharmacological

Crude marihuana extract: EEG and behavioral effects of chronic oral administration in Rhesus monkeys

Three Rhesus monkeys were treated daily po with crude marihuana extract (CME) containing δ9-THC 22–25%, cannabidiol 2–3% and cannabinol 2–3%, but no δ8-THC. CME with the equivalent of δ9-THC 12.5

Persistent Topographic Quantitative EEG Sequelae of Chronic Marihuana Use: A Replication Study and Initial Discriminant Function Analysis

A discriminant function analysis using quantitative EEG variables as candidate predictors generated a 95% correct THC user versus nonuser classification accuracy which received a successful jackknife replication.

Cannabis and the brain with special reference to the limbic system.

  • L. L. Miller
  • Psychology, Biology
    Advances in the biosciences
  • 1978

Electroencephalographic Studies of Substance Use and Abuse

This chapter provides an overview of the extant studies focusing on the acute and post-use effects of a selected number of drugs of abuse. This overview is not intended to provide an exhaustive



Comparison of tetrahydrocannabinol and synhexyl in man

These drugs differed from LSD in the following respects: sedation was prominent; euphoria was langer lasting; dreamlike sequences more pronounced; and physiological and biochemical effects were somewhat different, especially in the absence of sympathomimetic effects.