Marginal effects of glucose, insulin and insulin-like growth factor on chemotherapy response in endothelial and colorectal cancer cells

@inproceedings{Volkova2014MarginalEO,
  title={Marginal effects of glucose, insulin and insulin-like growth factor on chemotherapy response in endothelial and colorectal cancer cells},
  author={Ekaterina Volkova and Bridget Robinson and Jinny Willis and Margaret Currie and Gabi Ursula Dachs},
  booktitle={Oncology letters},
  year={2014}
}
Resistance to chemotherapy is a major clinical issue for patients with colorectal cancer. Obesity has been associated with a poorer outcome and is a possible mechanism of resistance. The aim of the present study was to investigate the effect of obesity-related factors on the cell response to standard chemotherapy in stromal and colorectal cancer cells. Viability was measured following the treatment of colorectal cancer cell lines (WiDr and SW620) and stromal cells (human microvascular… CONTINUE READING
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