Mapping vulnerability to bipolar disorder: a systematic review and meta-analysis of neuroimaging studies.

@article{FusarPoli2012MappingVT,
  title={Mapping vulnerability to bipolar disorder: a systematic review and meta-analysis of neuroimaging studies.},
  author={Paolo Fusar-Poli and Oliver D. Howes and Andreas Bechdolf and Stefan J. Borgwardt},
  journal={Journal of psychiatry \& neuroscience : JPN},
  year={2012},
  volume={37 3},
  pages={
          170-84
        }
}
BACKGROUND Although early interventions in individuals with bipolar disorder may reduce the associated personal and economic burden, the neurobiologic markers of enhanced risk are unknown. METHODS Neuroimaging studies involving individuals at enhanced genetic risk for bipolar disorder (HR) were included in a systematic review. We then performed a region of interest (ROI) analysis and a whole-brain meta-analysis combined with a formal effect-sizes meta-analysis in a subset of studies… 

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