Mapping the zebrafish brain methylome using reduced representation bisulfite sequencing

@inproceedings{Chatterjee2013MappingTZ,
  title={Mapping the zebrafish brain methylome using reduced representation bisulfite sequencing},
  author={Aniruddha Chatterjee and Yuichi Ozaki and Peter A. Stockwell and Julia A Horsfield and Ian M. Morison and Shinichi Nakagawa},
  booktitle={Epigenetics},
  year={2013}
}
Reduced representation bisulfite sequencing (RRBS) has been used to profile DNA methylation patterns in mammalian genomes such as human, mouse and rat. The methylome of the zebrafish, an important animal model, has not yet been characterized at base-pair resolution using RRBS. Therefore, we evaluated the technique of RRBS in this model organism by generating four single-nucleotide resolution DNA methylomes of adult zebrafish brain. We performed several simulations to show the distribution of… CONTINUE READING
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