Mapping the human genetic architecture of COVID-19

@article{NiemiKarjalainenLiaoNealeDalyGannaDavisLee202,
  title={Mapping the human genetic architecture of COVID-19},
  author={Mari E. K. Juha Rachel G. Benjamin M. Mark Andrea Lea S Niemi Karjalainen Liao Neale Daly Ganna Davis Lee and Mari E. K. Niemi and Juha Karjalainen and Rachel G Liao and Benjamin M. Neale and Mark Daly and Andrea Ganna and Lea K. Davis and Sulggi A. Lee and James R. Priest and Alessandra Renieri and Vijay G. Sankaran and David A. van Heel and Patrick Deelen and J. Brent Richards and Tomoko Nakanishi and Leslie G. Biesecker and Vern Eric Kerchberger and John Kenneth Baillie and Francesca Mari and Anna Bernasconi and Stefano Ceri Baillie and Arif Canakoglu and Xiao Chang and Joseph R. Glessner and Hakon Hakonarson},
  journal={Nature},
  year={2021},
  volume={600},
  pages={472 - 477}
}
  • Mari E. K. Juha Rachel G. Benjamin M. Mark Andrea Lea S Niemi Karjalainen Liao Neale Daly Ganna Davis Lee , M. Niemi, H. Hakonarson
  • Published 8 July 2021
  • Biology, Medicine
  • Nature
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We… 

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