Mapping the growth hormone--Stat5b--IGF-I transcriptional circuit.

  • Peter Rotwein
  • Published 2012 in Trends in endocrinology and metabolism: TEM


Growth hormone (GH) and insulin-like growth factor-I (IGF-I) exert powerful influences on somatic growth, metabolism, and tissue repair, and have been implicated in aging and carcinogenesis. Since the formulation of the somatomedin hypothesis over 50 years ago, GH and IGF-I have been linked intimately to one another. Recent studies have established that GH… (More)
DOI: 10.1016/j.tem.2012.01.001


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@article{Rotwein2012MappingTG, title={Mapping the growth hormone--Stat5b--IGF-I transcriptional circuit.}, author={Peter Rotwein}, journal={Trends in endocrinology and metabolism: TEM}, year={2012}, volume={23 4}, pages={186-93} }