Mapping the distribution of the outer hair cell motility voltage sensor by electrical amputation.

@article{Huang1993MappingTD,
  title={Mapping the distribution of the outer hair cell motility voltage sensor by electrical amputation.},
  author={G. J. Huang and Joseph Santos-Sacchi},
  journal={Biophysical journal},
  year={1993},
  volume={65 5},
  pages={2228-36}
}
The outer hair cell (OHC) possesses a nonlinear charge movement whose characteristics indicate that it represents the voltage sensor responsible for OHC mechanical activity. OHC mechanical activity is known to exist along a restricted extent of the cell's length. We have used a simultaneous partitioning microchamber and whole cell voltage clamp technique to electrically isolate sections of the OHC membrane and find that the nonlinear charge movement is also restricted along the cell's length… CONTINUE READING

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