Mapping the Stability Diagram of a Quadrupole Mass Spectrometer with a Static Transverse Magnetic Field Applied

@article{Maher2013MappingTS,
  title={Mapping the Stability Diagram of a Quadrupole Mass Spectrometer with a Static Transverse Magnetic Field Applied},
  author={Simon Maher and Sarfaraz U Syed and David M. Hughes and John Raymond Gibson and Stephen Taylor},
  journal={Journal of The American Society for Mass Spectrometry},
  year={2013},
  volume={24},
  pages={1307-1314}
}
AbstractPrevious experimental and theoretical work identified that the application of a static magnetic (B) field can improve the resolution of a quadrupole mass spectrometer (QMS) and this simple method of performance enhancement offers advantages for field deployment. Presented here are further data showing the effect of the transverse magnetic field upon the QMS performance. For the first time, the asymmetry in QMS operation with Bx and By is considered and explained in terms of operation in… 

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References

SHOWING 1-10 OF 22 REFERENCES

Effect of an axial magnetic field on the performance of a quadrupole mass spectrometer

Ion trajectories in quadrupole mass spectrometer with a static transverse magnetic field applied to mass filter

An experimental study has been carried out using a quadrupole mass spectrometer (QMS) in which a static magnetic field is applied transversely to the body of the filter. These results have been

Detailed simulation of mass spectra for quadrupole mass spectrometer systems

A method of computation to determine the trajectories of large numbers of ions in quadrupole mass spectrometers has been developed. The computer program produces simulated mass scans with over 105

Linear quadrupoles in mass spectrometry.

Extensions of quadrupole mass filters to higher masses, scanning with frequency sweeps of the quadrupoles waveform, operation in higher stability regions, and operation with rectangular or other periodic waveforms are discussed.

Effects of Mechanical Tolerances on QMF Performance for Operation in the Third Stability Zone

  • T. HoganS. Taylor
  • Materials Science
    IEEE Transactions on Instrumentation and Measurement
  • 2010
The results show that the direction of the electrode displacement, not the electrode, is the important factor in determining the effect on QMF performance, and that the effects of an individual electrode radius tolerance result in changes to the mass peak shape that are similar to those produced by individual electrode positional errors.

Factors Influencing the QMF Resolution for Operation in Stability Zones 1 and 3

A computer model is used to simulate a quadrupole mass filter (QMF) instrument under different operating conditions for Mathieu stability zones 1 and 3 and simulates well the linear and saturated regions of the performance curve for a range of operational conditions.

A miniature cylindrical quadrupole ion trap:  simulation and experiment.

A cylindrical quadrupole ion trap has been constructed, its geometry optimized, and its performance examined in the mass-selective instability scan mode to explore the effects of geometry on performance and to validate the experimental results.

A Method of Computing Accurate 3D Fields of a Quadrupole Mass Filter and Their Use for Prediction of Filter Behavior

A method is described that enables the three-dimensional fields of a simple quadrupole mass filter to be determined to a high accuracy and shows more complex variation with ion mass and other parameters than when fringe fields are ignored.