Mapping the Physiological Response of Oenococcus oeni to Ethanol Stress Using an Extended Genome-Scale Metabolic Model

@article{Contreras2018MappingTP,
  title={Mapping the Physiological Response of Oenococcus oeni to Ethanol Stress Using an Extended Genome-Scale Metabolic Model},
  author={{\'A}ngela Contreras and Magdalena Ribbeck and Guillermo D. Guti{\'e}rrez and Pablo M. Ca{\~n}{\'o}n and Sebasti{\'a}n N. Mendoza and Eduardo Agosin},
  journal={Frontiers in Microbiology},
  year={2018},
  volume={9}
}
The effect of ethanol on the metabolism of Oenococcus oeni, the bacterium responsible for the malolactic fermentation (MLF) of wine, is still scarcely understood. Here, we characterized the global metabolic response in O. oeni PSU-1 to increasing ethanol contents, ranging from 0 to 12% (v/v). We first optimized a wine-like, defined culture medium, MaxOeno, to allow sufficient bacterial growth to be able to quantitate different metabolites in batch cultures of O. oeni. Then, taking advantage of… Expand
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